MYC overexpression imposes a nonimmunogenic phenotype on Epstein–Barr virus-infected B cells

Lymphoblastoid cell lines, generated by immortalization of normal B cells by Epstein–Barr virus (EBV) in vitro, have strong antigen-presenting capacity, are sensitive to EBV-specific cytotoxic T cells, and are highly allostimulatory in mixed lymphocyte culture. By contrast, EBV-positive Burkitt lymp...

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Detalhes bibliográficos
Main Authors: Staege, Martin S., Lee, Steven P., Frisan, Teresa, Mautner, Josef, Scholz, Siegfried, Pajic, Alexander, Rickinson, Alan B., Masucci, Maria G., Polack, Axel, Bornkamm, Georg W.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123685/
https://ncbi.nlm.nih.gov/pubmed/11917131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072495599
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