Naive T cells proliferate strongly in neonatal mice in response to self-peptide/self-MHC complexes

Adult naive T cells, which are at rest in normal conditions, proliferate strongly when transferred to lymphopenic hosts. In neonates, the first mature thymocytes to migrate to the periphery reach a compartment devoid of preexisting T cells. We have extensively analyzed the proliferation rate and phe...

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Detalhes bibliográficos
Main Authors: Le Campion, Armelle, Bourgeois, Christine, Lambolez, Florence, Martin, Bruno, Léaument, Sandrine, Dautigny, Nicole, Tanchot, Corinne, Pénit, Claude, Lucas, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123683/
https://ncbi.nlm.nih.gov/pubmed/11917110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062621699
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