Naive T cells proliferate strongly in neonatal mice in response to self-peptide/self-MHC complexes

Adult naive T cells, which are at rest in normal conditions, proliferate strongly when transferred to lymphopenic hosts. In neonates, the first mature thymocytes to migrate to the periphery reach a compartment devoid of preexisting T cells. We have extensively analyzed the proliferation rate and phe...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Le Campion, Armelle, Bourgeois, Christine, Lambolez, Florence, Martin, Bruno, Léaument, Sandrine, Dautigny, Nicole, Tanchot, Corinne, Pénit, Claude, Lucas, Bruno
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123683/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11917110/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.062621699
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