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The accessory subunit of DNA polymerase γ is essential for mitochondrial DNA maintenance and development in Drosophila melanogaster

DNA polymerase γ, Pol γ, is the key replicative enzyme in animal mitochondria. The Drosophila enzyme is a heterodimer comprising catalytic and accessory subunits of 125 kDa and 35 kDa, respectively. Both subunits have been cloned and characterized in a variety of model systems, and genetic mutants o...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Iyengar, Balaji, Luo, Ningguang, Farr, Carol L., Kaguni, Laurie S., Campos, Ana Regina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2002
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Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123674/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11917141/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.072664899
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