Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

TGF-β can signal by means of Smad transcription factors, which are quintessential tumor suppressors that inhibit cell proliferation, and by means of Smad-independent mechanisms, which have been implicated in tumor progression. Although Smad mutations disable this tumor-suppressive pathway in certain...

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Main Authors: Kang, Yibin, He, Wei, Tulley, Shaun, Gupta, Gaorav P., Serganova, Inna, Chen, Chang-Rung, Manova-Todorova, Katia, Blasberg, Ronald, Gerald, William L., Massagué, Joan
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236573/
https://ncbi.nlm.nih.gov/pubmed/16172383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506517102
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