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Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons

The protein kinase A (PKA) and the cAMP response element (CRE) binding protein (CREB) signaling pathways mediate plasticity and prosurvival responses in neurons through their ability to regulate gene expression. The PKA–CREB signaling mechanism has been well characterized in terms of nuclear gene ex...

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Bibliografiske detaljer
Main Authors: Ryu, Hoon, Lee, Junghee, Impey, Soren, Ratan, Rajiv R., Ferrante, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236533/
https://ncbi.nlm.nih.gov/pubmed/16169904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502878102
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