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Mitochondrial Cyclic AMP Response Element-binding Protein (CREB) Mediates Mitochondrial Gene Expression and Neuronal Survival

Cyclic AMP response element-binding protein (CREB) is a widely expressed transcription factor whose role in neuronal protection is now well established. Here we report that CREB is present in the mitochondrial matrix of neurons and that it binds directly to cyclic AMP response elements (CREs) found...

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Detalhes bibliográficos
Main Authors: Lee, Junghee, Kim, Chun-Hyung, Simon, David K., Aminova, Lyaylya R., Andreyev, Alexander Y., Kushnareva, Yulia E., Murphy, Anne N., Lonze, Bonnie E., Kim, Kwang-Soo, Ginty, David D., Ferrante, Robert J., Ryu, Hoon, Ratan, Rajiv R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612541/
https://ncbi.nlm.nih.gov/pubmed/16207717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C500140200
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