Mitochondrial Cyclic AMP Response Element-binding Protein (CREB) Mediates Mitochondrial Gene Expression and Neuronal Survival

Cyclic AMP response element-binding protein (CREB) is a widely expressed transcription factor whose role in neuronal protection is now well established. Here we report that CREB is present in the mitochondrial matrix of neurons and that it binds directly to cyclic AMP response elements (CREs) found...

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Bibliografiske detaljer
Main Authors: Lee, Junghee, Kim, Chun-Hyung, Simon, David K., Aminova, Lyaylya R., Andreyev, Alexander Y., Kushnareva, Yulia E., Murphy, Anne N., Lonze, Bonnie E., Kim, Kwang-Soo, Ginty, David D., Ferrante, Robert J., Ryu, Hoon, Ratan, Rajiv R.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612541/
https://ncbi.nlm.nih.gov/pubmed/16207717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C500140200
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