Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro

Transcription-coupled repair (TCR) is essential for the rapid, preferential removal of DNA damage in active genes. The large subunit of RNA polymerase (Pol) II is ubiquitinated in cells after UV-irradiation or cisplatin treatment, which induces DNA damage preferentially repaired by TCR. Several huma...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Lee, Keng-Boon, Wang, Dong, Lippard, Stephen J., Sharp, Phillip A.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 2002
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123632/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11904382/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.072068399
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