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Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro

Transcription-coupled repair (TCR) is essential for the rapid, preferential removal of DNA damage in active genes. The large subunit of RNA polymerase (Pol) II is ubiquitinated in cells after UV-irradiation or cisplatin treatment, which induces DNA damage preferentially repaired by TCR. Several huma...

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Detalhes bibliográficos
Main Authors: Lee, Keng-Boon, Wang, Dong, Lippard, Stephen J., Sharp, Phillip A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123632/
https://ncbi.nlm.nih.gov/pubmed/11904382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072068399
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