Dual Roles for Spt5 in Pre-mRNA Processing and Transcription Elongation Revealed by Identification of Spt5-Associated Proteins

During transcription elongation, eukaryotic RNA polymerase II (Pol II) must contend with the barrier presented by nucleosomes. The conserved Spt4-Spt5 complex has been proposed to regulate elongation through nucleosomes by Pol II. To help define the mechanism of Spt5 function, we have characterized...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Lindstrom, D. L., Squazzo, S. L., Muster, N., Burckin, T. A., Wachter, K. C., Emigh, C. A., McCleery, J. A., Yates, J. R., Hartzog, G. A.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2003
Sujets:	Transcriptional Regulation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12556496/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.4.1368-1378.2003
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