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Surface-mediated enzymatic reactions: simulations of tissue factor activation of factor X on a lipid surface.

Blood coagulation proceeds via reactions in which zymogen coagulation factors are activated to proteases. An essential step is the activation of factor X by a complex of tissue factor and factor VIIa. This complex usually is studied using phospholipid vesicles into which tissue factor is inserted. B...

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Bibliographic Details
Main Authors: Gentry, R, Ye, L, Nemerson, Y
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236260/
https://ncbi.nlm.nih.gov/pubmed/8527649
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