Oligomerization and activation of caspase-9, induced by Apaf-1 CARD
Apaf-1 facilitates the proteolytic activation of procaspase-9 and maintains the hyperactive state of the processed caspase-9. The underlying molecular mechanisms for these activities remain poorly characterized. Here we report that the isolated Apaf-1 caspase recruitment domain (CARD) forms a large...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2002
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123625/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11904389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.072544399 |
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