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Mechanistic studies on DNA damage by minor groove binding copper–phenanthroline conjugates

Copper–phenanthroline complexes oxidatively damage and cleave nucleic acids. Copper bis-phenanthroline and copper complexes of mono- and bis-phenanthroline conjugates are used as research tools for studying nucleic acid structure and binding interactions. The mechanism of DNA oxidation and cleavage...

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Detalhes bibliográficos
Main Authors: Bales, Brian C., Kodama, Tetsuya, Weledji, Yvonne N., Pitié, Marguerite, Meunier, Bernard, Greenberg, Marc M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235636/
https://ncbi.nlm.nih.gov/pubmed/16186134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki856
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