A Genomewide Scan for Loci Predisposing to Type 2 Diabetes in a U.K. Population (The Diabetes UK Warren 2 Repository): Analysis of 573 Pedigrees Provides Independent Replication of a Susceptibility Locus on Chromosome 1q

Improved molecular understanding of the pathogenesis of type 2 diabetes is essential if current therapeutic and preventative options are to be extended. To identify diabetes-susceptibility genes, we have completed a primary (418-marker, 9-cM) autosomal-genome scan of 743 sib pairs (573 pedigrees) wi...

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Main Authors: Wiltshire, Steven, Hattersley, Andrew T., Hitman, Graham A., Walker, Mark, Levy, Jonathan C., Sampson, Michael, O’Rahilly, Stephen, Frayling, Timothy M., Bell, John I., Lathrop, G. Mark, Bennett, Amanda, Dhillon, Ranjit, Fletcher, Christopher, Groves, Christopher J., Jones, Elizabeth, Prestwich, Philip, Simecek, Nikol, Rao, Pamidighantam V. Subba, Wishart, Marie, Foxon, Richard, Howell, Simon, Smedley, Damian, Cardon, Lon R., Menzel, Stephan, McCarthy, Mark I.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2001
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235485/
https://ncbi.nlm.nih.gov/pubmed/11484155
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