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Variation in Cancer Risks, by Mutation Position, in BRCA2 Mutation Carriers

Cancer occurrence in 164 families with breast/ovarian cancer and germline BRCA2 mutations was studied to evaluate the evidence for genotype-phenotype correlations. Mutations in a central portion of the gene (the “ovarian cancer cluster region” [OCCR]) were associated with a significantly higher rati...

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Bibliografiska uppgifter
Huvudupphovsmän: Thompson, Deborah, Easton, Douglas
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society of Human Genetics 2001
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235274/
https://ncbi.nlm.nih.gov/pubmed/11170890
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