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Variation in Cancer Risks, by Mutation Position, in BRCA2 Mutation Carriers
Cancer occurrence in 164 families with breast/ovarian cancer and germline BRCA2 mutations was studied to evaluate the evidence for genotype-phenotype correlations. Mutations in a central portion of the gene (the “ovarian cancer cluster region” [OCCR]) were associated with a significantly higher rati...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society of Human Genetics
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1235274/ https://ncbi.nlm.nih.gov/pubmed/11170890 |
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