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Use of Closely Related Affected Individuals for the Genetic Study of Complex Diseases in Founder Populations

We propose a method, the maximum identity length contrast (MILC) statistic, to locate genetic risk factors for complex diseases in founder populations. The MILC approach compares the identity length of parental haplotypes that are transmitted to affected offspring with the identity length of those t...

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Bibliografiska uppgifter
Huvudupphovsmän: Bourgain, C., Génin, E., Holopainen, P., Mustalahti, K., Mäki, M., Partanen, J., Clerget-Darpoux, F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society of Human Genetics 2001
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234909/
https://ncbi.nlm.nih.gov/pubmed/11102286
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