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Consanguinity and the sib-pair method: an approach using identity by descent between and within individuals.

To test for linkage between a trait and a marker, one can consider identical marker alleles in related individuals, for instance, sibs. For recessive diseases, it has been shown that some information may be gained from the identity by descent (IBD) of the two alleles of an affected inbred individual...

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Detalhes bibliográficos
Main Authors: Génin, E., Clerget-Darpoux, F.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914848/
https://ncbi.nlm.nih.gov/pubmed/8900245
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