Enhanced Expression of an α2,6-Linked Sialic Acid on MDCK Cells Improves Isolation of Human Influenza Viruses and Evaluation of Their Sensitivity to a Neuraminidase Inhibitor

The extensive use of neuraminidase (NA) inhibitors to treat influenza virus infections mandates close monitoring for resistant variants. Cultured cells do not provide a reliable means of evaluating the susceptibility of human influenza virus isolates to NA inhibitors. That is, the growth of such vir...

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Detalhes bibliográficos
Main Authors: Hatakeyama, Shuji, Sakai-Tagawa, Yuko, Kiso, Maki, Goto, Hideo, Kawakami, Chiharu, Mitamura, Keiko, Sugaya, Norio, Suzuki, Yasuo, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2005
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1233980/
https://ncbi.nlm.nih.gov/pubmed/16081961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.43.8.4139-4146.2005
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