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Deletion of immunoglobulin β in developing B cells leads to cell death

Inducible gene-targeting experiments have shown that Igμ expression is essential for maintaining survival of mature B cells, but the role of Igμ expression in immature B cell survival has not been determined. To assess whether continued B cell receptor (BCR) expression is required for bone marrow B...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Proc Natl Acad Sci U S A
Ngā kaituhi matua: Meffre, Eric, Nussenzweig, Michel C.
Hōputu: Artigo
Reo:Inglês
I whakaputaina: National Academy of Sciences 2002
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123257/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12165571/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.172369999
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