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Deletion of immunoglobulin β in developing B cells leads to cell death

Inducible gene-targeting experiments have shown that Igμ expression is essential for maintaining survival of mature B cells, but the role of Igμ expression in immature B cell survival has not been determined. To assess whether continued B cell receptor (BCR) expression is required for bone marrow B...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Meffre, Eric, Nussenzweig, Michel C.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123257/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12165571/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.172369999
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