Identification of HLA-E-specific alloreactive T lymphocytes: A cell subset that undergoes preferential expansion in mixed lymphocyte culture and displays a broad cytolytic activity against allogeneic cells

Previous studies showed that a subset of CD8(+) cytolytic T lymphocytes expressing HLA class I-specific natural killer inhibitory receptors (iNKR) is characterized by the ability to recognize HLA-E and to mediate T cell receptor-dependent killing of different NK cell-susceptible tumor target cells....

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Hauptverfasser: Romagnani, Chiara, Pietra, Gabriella, Falco, Michela, Millo, Enrico, Mazzarino, Paola, Biassoni, Roberto, Moretta, Alessandro, Moretta, Lorenzo, Mingari, Maria Cristina
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2002
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC123256/
https://ncbi.nlm.nih.gov/pubmed/12167676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172369799
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