A nuclear export signal within the high mobility group domain regulates the nucleocytoplasmic translocation of SOX9 during sexual determination

In mammals, male sex determination starts when the Y chromosome Sry gene is expressed within the undetermined male gonad. One of the earliest effect of Sry expression is to induce up-regulation of Sox9 gene expression in the developing gonad. SOX9, like SRY, contains a high mobility group domain and...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Gasca, Stéphan, Cañizares, Joaquin, de Santa Barbara, Pascal, Méjean, Catherine, Poulat, Francis, Berta, Philippe, Boizet-Bonhoure, Brigitte
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2002
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12169669/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.172383099
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