Two distinct modes of RecA action are required for DNA polymerase V-catalyzed translesion synthesis

SOS mutagenesis in Escherichia coli requires DNA polymerase V (pol V) and RecA protein to copy damaged DNA templates. Here we show that two distinct biochemical modes for RecA protein are necessary for pol V-catalyzed translesion synthesis. One RecA mode is characterized by a strong stimulation in n...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Pham, Phuong, Seitz, Erica M., Saveliev, Sergei, Shen, Xuan, Woodgate, Roger, Cox, Michael M., Goodman, Myron F.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123210/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12177433/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.172197099
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