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Tyrosine sulfation of CCR5 N-terminal peptide by tyrosylprotein sulfotransferases 1 and 2 follows a discrete pattern and temporal sequence

The CC-chemokine receptor 5 (CCR5) is the major coreceptor for the entry of macrophage-tropic (R5) HIV-1 strains into target cells. Posttranslational sulfation of tyrosine residues in the N-terminal tail of CCR5 is critical for high affinity interaction of the receptor with the HIV-1 envelope glycop...

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Detalhes bibliográficos
Main Authors: Seibert, Christoph, Cadene, Martine, Sanfiz, Anthony, Chait, Brian T., Sakmar, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123205/
https://ncbi.nlm.nih.gov/pubmed/12169668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172380899
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