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DNA detection using water-soluble conjugated polymers and peptide nucleic acid probes

The light-harvesting properties of cationic conjugated polymers are used to sensitize the emission of a dye on a specific peptide nucleic acid (PNA) sequence for the purpose of homogeneous, “real-time” DNA detection. Signal transduction is controlled by hybridization of the neutral PNA probe and the...

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Detalhes bibliográficos
Main Authors: Gaylord, Brent S., Heeger, Alan J., Bazan, Guillermo C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123191/
https://ncbi.nlm.nih.gov/pubmed/12167673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162375999
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