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C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity
C75, a known inhibitor of fatty acid synthase is postulated to cause significant weight loss through decreased hypothalamic neuropeptide Y (NPY) production. Peripherally, C75, an α-methylene-γ-butyrolactone, reduces adipose tissue and fatty liver, despite high levels of malonyl-CoA. To investigate t...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123169/ https://ncbi.nlm.nih.gov/pubmed/12060712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132128899 |
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