Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization

Osteoblasts mineralize bone matrix by promoting hydroxyapatite crystal formation and growth in the interior of membrane-limited matrix vesicles (MVs) and by propagating the crystals onto the collagenous extracellular matrix. Two osteoblast proteins, tissue-nonspecific alkaline phosphatase (TNAP) and...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Hessle, Lovisa, Johnson, Kristen A., Anderson, H. Clarke, Narisawa, Sonoko, Sali, Adnan, Goding, James W., Terkeltaub, Robert, Millán, José Luis
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 2002
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12082181/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.142063399
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