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Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1
Human IL-10 (hIL-10) modulates critical immune and inflammatory responses by way of interactions with its high- (IL-10R1) and low-affinity (IL-10R2) cell surface receptors. Human cytomegalovirus exploits the IL-10 signaling pathway by expressing a functional viral IL-10 homolog (cmvIL-10), which sha...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123153/ https://ncbi.nlm.nih.gov/pubmed/12093920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152147499 |
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