Promoter-proximal tethering elements regulate enhancer-promoter specificity in the Drosophila Antennapedia complex

Insulator DNAs and promoter competition regulate enhancer–promoter interactions within complex genetic loci. Here we provide evidence for a third mechanism: promoter-proximal tethering elements. The Scr-ftz region of the Antennapedia gene complex includes two known enhancers, AE1 and T1. AE1 selecti...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Calhoun, Vincent C., Stathopoulos, Angelike, Levine, Michael
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123125/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093913/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.142291299
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!