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Promoter-proximal tethering elements regulate enhancer-promoter specificity in the Drosophila Antennapedia complex

Insulator DNAs and promoter competition regulate enhancer–promoter interactions within complex genetic loci. Here we provide evidence for a third mechanism: promoter-proximal tethering elements. The Scr-ftz region of the Antennapedia gene complex includes two known enhancers, AE1 and T1. AE1 selecti...

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Detalhes bibliográficos
Main Authors: Calhoun, Vincent C., Stathopoulos, Angelike, Levine, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123125/
https://ncbi.nlm.nih.gov/pubmed/12093913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.142291299
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