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Pheromone induction promotes Ste11 degradation through a MAPK feedback and ubiquitin-dependent mechanism

Ste11 is the mitogen-activated protein kinase (MAPK) kinase kinase in the MAPK cascades that mediate mating, high osmolarity glycerol, and filamentous growth responses in Saccharomyces cerevisiae. We show stimulation of the mating pathway by pheromone promotes an accelerated turnover of Ste11 throug...

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Bibliografiske detaljer
Main Authors: Esch, R. K., Errede, B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC123111/
https://ncbi.nlm.nih.gov/pubmed/12077316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.142034399
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