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A ribozyme that ligates RNA to protein

We have used a combination of in vitro selection and rational design to generate ribozymes that form a stable phosphoamide bond between the 5′ terminus of an RNA and a specific polypeptide. This reaction differs from that of previously identified ribozymes, although the product is analogous to the e...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Baskerville, Scott, Bartel, David P.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123110/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12077317/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.142153799
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