Induction of Protective Immunity to Anthrax Lethal Toxin with a Nonhuman Primate Adenovirus-Based Vaccine in the Presence of Preexisting Anti-Human Adenovirus Immunity

Prevention or therapy for bioterrorism-associated anthrax infections requires rapidly acting effective vaccines. We recently demonstrated (Y. Tan, N. R. Hackett, J. L. Boyer, and R. G. Crystal, Hum. Gene Ther. 14:1673-1682, 2003) that a single administration of a recombinant serotype 5 adenovirus (A...

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Autori principali: Hashimoto, Masahiko, Boyer, Julie L., Hackett, Neil R., Wilson, James M., Crystal, Ronald G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230977/
https://ncbi.nlm.nih.gov/pubmed/16177368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6885-6891.2005
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