An Anthrax Lethal Factor-Neutralizing Monoclonal Antibody Protects Rats before and after Challenge with Anthrax Toxin

Lethal factor (LF) is a component of anthrax lethal toxin (LeTx). We generated anti-LF murine monoclonal antibodies (MAbs) that show LeTx-neutralizing activity in vitro and in vivo. Anti-LF MAbs were generated by immunization with recombinant LF, and the MAbs showing LeTx-neutralizing activity in vi...

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Autors principals: Lim, Nam-Kyu, Kim, Jung-Hwan, Oh, Mee Sook, Lee, Sangyoon, Kim, Se-Yeon, Kim, Keun-Soo, Kang, Hyun-jung, Hong, Hyo Jeong, Inn, Kyung-Soo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230968/
https://ncbi.nlm.nih.gov/pubmed/16177329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6547-6551.2005
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