NK Cells in Gamma-Interferon-Deficient Mice Suppress Lung Innate Immunity against Mycoplasma spp.

The purpose of this study was to examine the 100-fold difference in mycoplasma levels in lungs of gamma interferon knockout (IFN-γ(−/−)) mice compared to those seen with wild-type BALB/c mice at 3 days postinfection. NK cells secreted IFN-γ; however, their cytotoxic granule extracts failed to kill m...

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Detalhes bibliográficos
Main Authors: Woolard, Matthew D., Hudig, Dorothy, Tabor, Leslie, Ivey, James A., Simecka, Jerry W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230952/
https://ncbi.nlm.nih.gov/pubmed/16177352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6742-6751.2005
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