Phagocytosis of Borrelia burgdorferi and Treponema pallidum Potentiates Innate Immune Activation and Induces Gamma Interferon Production

We examined the interactions of live and lysed spirochetes with innate immune cells. THP-1 monocytoid cells were activated to comparable extents by live Borrelia burgdorferi and by B. burgdorferi and Treponema pallidum lysates but were poorly activated by live T. pallidum. Because THP-1 cells poorly...

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Hlavní autoři: Moore, Meagan W., Cruz, Adriana R., LaVake, Carson J., Marzo, Amanda L., Eggers, Christian H., Salazar, Juan C., Radolf, Justin D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865718/
https://ncbi.nlm.nih.gov/pubmed/17220323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01666-06
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