All-trans-retinal shuts down rod cyclic nucleotide-gated ion channels: A novel role for photoreceptor retinoids in the response to bright light?

In retinal rods, light-induced isomerization of 11-cis-retinal to all-trans-retinal within rhodopsin triggers an enzyme cascade that lowers the concentration of cGMP. Consequently, cyclic nucleotide-gated (CNG) ion channels close, generating the first electrical response to light. After isomerizatio...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Dean, Dylan M., Nguitragool, Wang, Miri, Andrew, McCabe, Sarah L., Zimmerman, Anita L.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC123074/
https://ncbi.nlm.nih.gov/pubmed/12034887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122681899
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares