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A genetically clamped renin transgene for the induction of hypertension

Experimental analysis of the effects of individual components of complex mammalian systems is frequently impeded by compensatory adjustments that animals make to achieve homeostasis. We here introduce a genetic procedure for eliminating this type of impediment, by using as an example the development...

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Detalles Bibliográficos
Main Authors: Caron, Kathleen M. I., James, Leighton R., Kim, Hyung-Suk, Morham, Scott G., Lopez, Maria Luisa S. Sequeira, Gomez, R. Ariel, Reudelhuber, Timothy L., Smithies, Oliver
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC123053/
https://ncbi.nlm.nih.gov/pubmed/12034874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112222199
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