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Chromosome translocations and covert leukemic clones are generated during normal fetal development

Studies on monozygotic twins with concordant leukemia and retrospective scrutiny of neonatal blood spots of patients with leukemia indicate that chromosomal translocations characteristic of pediatric leukemia often arise prenatally, probably as initiating events. The modest concordance rate for leuk...

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Detalhes bibliográficos
Main Authors: Mori, Hiroshi, Colman, Susan M., Xiao, Zhijian, Ford, Anthony M., Healy, Lyn E., Donaldson, Craig, Hows, Jill M., Navarrete, Cristina, Greaves, Mel
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123052/
https://ncbi.nlm.nih.gov/pubmed/12048236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112218799
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