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Specificity requirements for selection and effector functions of CD25(+)4(+) regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice
CD25(+)4(+) regulatory T cells (T(reg)) play an indispensable role in preventing autoimmunity. Little is known, however, about the antigen specificities required for their development and effector functions. Mice transgenic for an anti-myelin basic protein (MBP) T cell antigen receptor (TCR) spontan...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123047/ https://ncbi.nlm.nih.gov/pubmed/12034883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122224799 |
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