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Autoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif

The GGAs (Golgi-localizing, γ-adaptin ear homology domain, ARF-binding proteins) are a family of proteins implicated in protein trafficking from the Golgi to endosomes/lysosomes. These proteins have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and T...

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Detaylı Bibliyografya
Asıl Yazarlar: Doray, Balraj, Bruns, Kerry, Ghosh, Pradipta, Kornfeld, Stuart A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC123022/
https://ncbi.nlm.nih.gov/pubmed/12060753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082235699
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