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DT40 cells lacking the Ca(2+)-binding protein annexin 5 are resistant to Ca(2+)-dependent apoptosis
Annexins are widely expressed Ca(2+)-dependent phospholipid-binding proteins with poorly understood physiological roles. Proposed functions include Ca(2+) channel activity and vesicle trafficking, but neither have been proven in vivo. Here we used targeted gene disruption to generate B-lymphocytes l...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123019/ https://ncbi.nlm.nih.gov/pubmed/12060752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132598099 |
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