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DT40 cells lacking the Ca(2+)-binding protein annexin 5 are resistant to Ca(2+)-dependent apoptosis

Annexins are widely expressed Ca(2+)-dependent phospholipid-binding proteins with poorly understood physiological roles. Proposed functions include Ca(2+) channel activity and vesicle trafficking, but neither have been proven in vivo. Here we used targeted gene disruption to generate B-lymphocytes l...

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Detalhes bibliográficos
Main Authors: Hawkins, Timothy E., Das, Debipriya, Young, Barry, Moss, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123019/
https://ncbi.nlm.nih.gov/pubmed/12060752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132598099
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