Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites

Runx factors control lineage commitment and are transcriptional effectors of Smad signaling. Genetic defects in these pathways interfere with normal development. The in situ localization of Runx and Smad proteins must impact the mechanisms by which these proteins function together in gene regulation...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Zaidi, Sayyed K., Sullivan, Andrew J., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Lian, Jane B.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123018/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12060751/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.112664499
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