Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486

Selective receptor modulators, such as the antiprogestin RU486, are known to exhibit partial agonist activities in a cell-type-dependent manner. Employing an in vitro chromatin transcription system that recapitulates progesterone receptor (PR)-mediated transcription in vivo, we have investigated the...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Liu, Zheng, Auboeuf, Didier, Wong, Jiemin, Chen, J. Don, Tsai, Sophia Y., Tsai, Ming-Jer, O'Malley, Bert W.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 2002
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12048256/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.122225699
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