Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486

Selective receptor modulators, such as the antiprogestin RU486, are known to exhibit partial agonist activities in a cell-type-dependent manner. Employing an in vitro chromatin transcription system that recapitulates progesterone receptor (PR)-mediated transcription in vivo, we have investigated the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Zheng, Auboeuf, Didier, Wong, Jiemin, Chen, J. Don, Tsai, Sophia Y., Tsai, Ming-Jer, O'Malley, Bert W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 2002
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC122999/
https://ncbi.nlm.nih.gov/pubmed/12048256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122225699
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