p38 is essential for the assembly and stability of macromolecular tRNA synthetase complex: Implications for its physiological significance

Mammalian tRNA synthetases form a macromolecular complex with three nonenzyme factors: p43, p38, and p18. Here we introduced a mutation within the mouse p38 gene to understand its functional significance for the formation of the multi-tRNA synthetase complex. The complex was completely disintegrated...

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Detalhes bibliográficos
Main Authors: Kim, Jin Young, Kang, Young-Sun, Lee, Joong-Won, Kim, Hyoung June, Ahn, Young Ha, Park, Heonyong, Ko, Young-Gyu, Kim, Sunghoon
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122994/
https://ncbi.nlm.nih.gov/pubmed/12060739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122110199
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