Hemagglutinin sequence clusters and the antigenic evolution of influenza A virus
Continual mutations to the hemagglutinin (HA) gene of influenza A virus generate novel antigenic strains that cause annual epidemics. Using a database of 560 viral RNA sequences, we study the structure and tempo of HA evolution over the past two decades. We detect a critical length scale, in amino a...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2002
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122937/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11972025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.082110799 |
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