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Differential regulation of the human and murine CD34 genes in hematopoietic stem cells

Human CD34 (hCD34)-positive cells are used currently as a source for hematopoietic transplantation in humans. However, in steady-state murine hematopoiesis, hematopoietic stem cells (HSCs) with long-term reconstitution activity are found almost exclusively in the murine CD34 (mCD34)-negative to low...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Okuno, Yutaka, Iwasaki, Hiromi, Huettner, Claudia S., Radomska, Hanna S., Gonzalez, David A., Tenen, Daniel G., Akashi, Koichi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122934/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11983914/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.092027799
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