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Hematopoietic stem and progenitor cells are differentially mobilized depending on the duration of Flt3-ligand administration

Background Flt3-ligand is a cytokine that induces relatively slow mobilization of hematopoietic cells in animals and humans in vivo. This provides a time-frame to study hematopoietic stem and progenitor cell migration kinetics in detail.Design and Methods Mice were injected with Flt3-ligand (10 μg/d...

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Principais autores: Evert-Jan F.M. de Kruijf, Henny Hagoort, Gerjo A. Velders, Willem E. Fibbe, Melissa van Pel
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2010-07-01
Serier:Haematologica
Online adgang:https://haematologica.org/article/view/5646
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